Title of article
Functionalized polyvinyl alcohol derivatives thin films for controlled drug release and targeting systems: MAPLE deposition and morphological, chemical and in vitro characterization
Author/Authors
R. Cristescu، نويسنده , , C. Popescu، نويسنده , , A.C. Popescu، نويسنده , , S. Grigorescu، نويسنده , , L. Duta، نويسنده , , Shyh-Lin Tsao and I.N. Mihailescu، نويسنده , , G. Caraene، نويسنده , , R. Albulescu، نويسنده , , L. Albulescu، نويسنده , , A. Andronie، نويسنده , , I. Stamatin، نويسنده , , Despina A. Ionescu، نويسنده , , D. Mihaiescu and A. Moldovan، نويسنده , , T. Buruiana، نويسنده , , D.B. Chrisey، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2009
Pages
5
From page
5600
To page
5604
Abstract
We report thin film deposition of polyvinyl alcohol functionalized with carboxylic groups bound to aromatic nucleus (PVACOOH) by matrix-assisted pulsed laser evaporation (MAPLE). We used a KrF* excimer laser source (λ = 248 nm, τ = 25 ns, image). The obtained thin films have been investigated by FTIR, AFM, and in vitro tests. We identified the best compromise between the parameters of laser processing and characteristics of nanostructured thin films of PVACOOH in terms of porosity and similar composition with those of starting material.
Keywords
In vitro , Controlled drug release , Matrix-assisted pulsed laser evaporation , Porous polymers
Journal title
Applied Surface Science
Serial Year
2009
Journal title
Applied Surface Science
Record number
1011344
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