• Title of article

    A Stress Sensor for the Bacterial Periplasm

  • Author/Authors

    Jason C. Young، نويسنده , , Andreas Bracher and F. Ulrich Hartl، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2003
  • Pages
    2
  • From page
    1
  • To page
    2
  • Abstract
    DegS, the periplasmic stress sensor, becomes activated when its PDZ domain recognizes the improperly exposed C-terminal sequences of outer membrane porins. This interaction relieves the inhibition of the neighboring protease domain of DegS, triggering a proteolysis cascade that leads to the σE-driven expression of periplasmic chaperones.
  • Journal title
    CELL
  • Serial Year
    2003
  • Journal title
    CELL
  • Record number

    1018165

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1018165