Title of article :
DNA Cytosine Demethylation: Are We Getting Close?
Author/Authors :
Josef Jiricny and Fritz K. Winkler، نويسنده , , Mirco Menigatti، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
Whether 5-methylcytosine (meC) can be enzymatically removed from vertebrate DNA has been the subject of extensive study and also some controversy. now report that cytosine demethylation can be accomplished in a one-cell zebrafish embryo by the combined action of a cytidine deaminase and a thymine DNA glycosylase.
