Title of article :
A New Therapeutic Target for Leukemia Comes to the Surface
Author/Authors :
David S. Ritchie، نويسنده , , Mark J. Smyth، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
Expression of the cell-surface protein CD47 allows some normal cells to avoid phagocytosis by macrophages. In this issue, and show that elevated CD47 expression by leukemic stem cells inhibits macrophage activity and is an indicator of poor prognosis for patients with acute myeloid leukemia.
