Title of article :
Putting Two Heads Together to Unwind DNA
Author/Authors :
Thomas J. Takara، نويسنده , , Stephen P. Bell، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
The loading of replicative helicases onto DNA is tightly regulated in all organisms, yet the molecular mechanisms for this event remain poorly defined. provide important insights into helicase loading in eukaryotes, showing that the Mcm2–7 replicative helicase encircles double-stranded DNA as head-to-head double hexamers.
