Title of article :
The Immunoproteasome Cleans up after Inflammation
Author/Authors :
Sjoerd van Deventer، نويسنده , , Jacques Neefjes، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
Immune cells and cells activated by the inflammatory cytokine interferon express variant proteasomes called immunoproteasomes that are characterized by unique catalytic subunits. now show in mouse models of inflammatory disease that immunoproteasomes help prevent the accumulation of harmful protein aggregates.