Title of article :
Targeting Aneuploidy for Cancer Therapy
Author/Authors :
Eusebio Manchado، نويسنده , , Marcos Malumbres، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Tumor cells frequently display an abnormal number of chromosomes, a phenomenon known as aneuploidy. now show that aneuploid cells are particularly sensitive to compounds that induce proteotoxic and energy stress. Could this vulnerability lead to new cancer therapies?