Title of article
DNA-Damage-Induced Differentiation in Hematopoietic Stem Cells
Author/Authors
Pankaj K. Mandal، نويسنده , , Derrick J. Rossi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
2
From page
847
To page
848
Abstract
Aging of hematopoietic stem cells (HSCs) is accompanied by diminished functional potential. Wang et al. now provide evidence for an HSC-specific differentiation checkpoint mediated by the transcription factor BATF, which limits self-renewal of HSCs in response to the accumulation of DNA damage.
Journal title
CELL
Serial Year
2012
Journal title
CELL
Record number
1021070
Link To Document