Title of article :
Synovial Sarcoma Mechanisms: A Series of Unfortunate Events
Author/Authors :
Jesper Q. Svejstrup، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
Human synovial sarcoma is caused by a chromosome translocation, which fuses DNA encoding SSX to that encoding the SS18 protein. Kadoch and Crabtree now show that the resulting cellular transformation stems from disruption of the normal architecture and function of the human SWI/SNF (BAF) complex.
