Abstract :
On June 5, 2013, Ruslan Medzhitov received the Else Kröner-Fresenius Immunology Award. This recognition goes to an individual who has had such an influence on basic and medical immunology that it is almost difficult to recall a time before his discoveries were made. But in reality, that time was not long ago. To mark this celebratory event, I highlight the conceptual revolution spurred by his work, which continues to inspire excitement today.