One-pot Synthesis of New Benzofurane-Chatecholamine Derivatives by Electrochemical Method

The electrochemical oxidation of some catechols has been studied in the presence of N-phenylacetoacetamide in aqueous sodium phosphate buffer (pH=7), using cyclic voltammetry and controlled-potential coulometry. All the catechol derivatives were converted into benzofuran derivatives through a Michael-type addition reaction of N-phenylacetoacetamide to anodically generated o-quinones. The electrochemical syntheses benzofuran derivatives of were successfully performed in one pot in an undivided cell using an environmentally friendly method .