Author/Authors :
ElGhobashy، Mohamed Refaat نويسنده Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr-El-Aini 11562, Cairo, Egypt , , Badran، Osama Mohamed نويسنده Analytical chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., ET-11562 Cairo, Egypt , , Salem، Maissa Yacoub نويسنده Analytical chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini St.,Egypt , , Kelani، Khadiga Mohamed نويسنده Analytical chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini St.,Egypt ,
Abstract :
Azelastine Hydrochloride (AZT) was described by using the ion association
complex between these drugs with either sodium tetraphenyl-borate (TPB) or ammonium
reineckate (RNC) counter ions. The performance characteristics of the sensors were evaluated
according to IUPAC recommendations, reveal a fast, stable and linear response over the
concentration range 10-5- 10-2 M for AZT. The sensors are used for determination of AZT in
eye drops and plasma. The developed method was found to be simple, accurate and precise
when compared with the Manufacturer method.
