Title of article
Application of Membrane Selective Electrodes for the Determination of Azelastine Hydrochloride in the Presence of its Alkaline Degradant in Eye Drops and Plasma
Author/Authors
ElGhobashy، Mohamed Refaat نويسنده Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr-El-Aini 11562, Cairo, Egypt , , Badran، Osama Mohamed نويسنده Analytical chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., ET-11562 Cairo, Egypt , , Salem، Maissa Yacoub نويسنده Analytical chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini St.,Egypt , , Kelani، Khadiga Mohamed نويسنده Analytical chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Aini St.,Egypt ,
Issue Information
دوماهنامه با شماره پیاپی سال 2013
Pages
16
From page
325
To page
340
Abstract
Azelastine Hydrochloride (AZT) was described by using the ion association
complex between these drugs with either sodium tetraphenyl-borate (TPB) or ammonium
reineckate (RNC) counter ions. The performance characteristics of the sensors were evaluated
according to IUPAC recommendations, reveal a fast, stable and linear response over the
concentration range 10-5- 10-2 M for AZT. The sensors are used for determination of AZT in
eye drops and plasma. The developed method was found to be simple, accurate and precise
when compared with the Manufacturer method.
Journal title
Analytical and Bioanalytical Electrochemistry
Serial Year
2013
Journal title
Analytical and Bioanalytical Electrochemistry
Record number
1025689
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