Author/Authors :
Shankar، S. Sharath نويسنده Department of P.G. Studies and Research in Industrial Chemistry, Kuvempu University, JnanaSahyadri, Shankaraghatta-577 451, Karnataka, India Shankar, S. Sharath , Kumara Swamy، Bahaddurghatta E. نويسنده Department of P.G. Studies and Research in Industrial Chemistry, Kuvempu University, Jnana Sahyadri, Shankaraghatta, Shimoga, Karnataka 577451, India , , Mahanthesha، Kurangalara R. نويسنده Department of PG Studies and Research in Industrial Chemistry, Kuvempu University, Shankaraghatta 577451, Shimoga, Karnataka, India , , Vishwanatha، Chandrashekar C نويسنده Department of P.G. Studies and Research in Industrial Chemistry, Kuvempu University, JnanaSahyadri, Shankaraghatta-577 451, Karnataka, India Vishwanatha, Chandrashekar C , Kumar، M. S. Mohan نويسنده ,
Abstract :
A cationic surfactant tetradecyl trimethyl ammonium bromide modified carbon
pasteelectrode (TTABMCPE) was fabricated and the electrochemical behavior of
norepinephrine at the modified electrode was investigated by cyclic voltammetric and
differential pulse voltammetric techniques. A well-defined oxidation peak was observed at
174 mV and the significant increase in peak current at modified carbon paste electrode
compared to bare carbon paste electrode was obtained. The effect of scan rate on the
oxidation of norepinephrine was examined and it was found that the anodic peak current was
proportional to the concentration of norepinephrine in the range from 0.10 ?M to 4 ?M.
Comparedwith other reported electrochemical method; this new sensingmethod has higher
sensitivity, rapid response and extreme simplicity. TTABMCPE was used for the
simultaneous determination of nor norepinephrine, ascorbic acid and uric acid.The analytical
performance of this biosensor has been evaluated for the detection of norepinephrine in
injection sample
