Hot eluent capillary liquid chromatography using zirconia and titania based stationary phases Original Research Article

High speed capillary liquid chromatographic separations using a simple home made system constructed from readily available inexpensive components have been studied. Using thermally stable zirconia and titania based packing, the separation of eight alkylbenzene derivatives in less than 2 min is shown. The system is capable of operating at temperatures as high as 200°C and pressures up to 10,000 psi and can, thus, take advantage of the reduction in eluent viscosity and enhanced mass transport at elevated temperatures to operate at very high linear velocities without sacrificing separation efficiency.