Advantages and disadvantages of nuclear magnetic resonance spectroscopy as a hyphenated technique Review Article

A general overview of the advancements and applications of nuclear magnetic resonance (NMR) hyphenated with other analytical techniques is given from a practical point of view. Details on the advantages and disadvantages of the hyphenation of NMR with liquid chromatography as LC–NMR and also with mass spectrometry as LC–MS–NMR are demonstrated with two examples. Current developments of NMR with other analytical separation techniques, especially with capillary liquid chromatography (capLC) are discussed.