Author/Authors :
Davoodi، Sayed Hossain نويسنده Dept. of Clinical Nutrition and Dietetics, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences, Food Science a , , Malek-Shahabi، Talieh نويسنده Dept. of Molecular genetics, Shahid Beheshti University, Tehran, Iran , , Malekshahi-Moghadam، Ali نويسنده Faculty of Veterinary Medicine, Tehran University , Tehran, Iran , , Shahbazi، Roghieh نويسنده Dept. of Clinical Nutrition and Dietetics, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences, Food Science a , , Esmaeili، Saeideh نويسنده Department of Food Technology Research, National Nutrition and Food Technology Research Institute, Faculty of Nutrition and Food Technology, Shahid Esmaeili, Saeideh
Abstract :
Cancer could be described as the uncontrolled and unrestricted growth of malignant cells in any place of the body. It is a multifactorial disease which either heredity or environmental factors (such as nutrition, physical inactivity, alcohol, obesity, exposure to sun, environmental pollutants, infections) chip in incidence of cancer. In recent years, several researchers have focused on obesity as a potent cancer risk factor. Scientific evidences have suggested that obesity has associated with increased risk for a plenty of different types of cancer. The evidences are the most consistent for endometrial cancer, breast cancer between the postmenopausal women, and renal cell cancer. More contradictory results have reported about the colorectal, prostate, and pancreatic cancer. Although numerous studies have done according to the obesity and cancer relation or joint, but The molecular mechanisms in which obesity could increase the risks of cancer, have been poorly understood.