Author/Authors :
Kap?on، Katarzyna نويسنده Department of Organic Chemistry, Maria Curie-Sk?odowska University, 33 - Gliniana Street, 20-614 Lublin, Poland , , Demchuk، Oleg M. نويسنده Department of Organic Chemistry, Maria Curie-Sk?odowska University, 33 - Gliniana Street, 20-614 Lublin, Poland , , Wieczorek، Marta نويسنده Department of Organic Chemistry, Maria Curie-Sk?odowska University, 33 - Gliniana Street, 20-614 Lublin, Poland , , Pietrusiewicz، K. Micha? نويسنده Department of Organic Chemistry, Maria Curie-Sk?odowska University, 33 - Gliniana Street, 20-614 Lublin, Poland ,
Abstract :
An inexpensive straightforward approach to direct oxidative twofold C-H arylation of 1,4-naphthoquinone catalyzed by readily available Br?nsted acids was developed. Under the simple and easily achievable reaction conditions, electron-rich aromatics undergo Friedel-Crafts type functionalization to furnish 2-arylonaphthoquinones in good yields. The attempt to rationalize the scope and limitation of the approach based on desktop PC DFT calculation and reactivity indexes theory was taken up.
