Title of article :
A Stereoselective Synthesis of α-(1-Hydroxyalkyl)-β-Substituted Acrylic Acid Esters
Author/Authors :
Taïcir Ben Ayed، نويسنده , , Jean Villiéras، نويسنده , , Hassen Amri، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
Nucleophilic substitution of vinylic iodide of methyl 2-(1-hydroxyalkyl)-3-iodo prop-2-enoates 8 in the presence of magnesium dialkyl cuprates generated in situ provided a stereoselective methodology for the synthesis of infrequent β-substituted Baylis–Hillman products.
Keywords :
Baylis–Hillman products , Cuprates , Nucleophilic substitution , Stereoselectivity
Journal title :
Tetrahedron
Journal title :
Tetrahedron
