Title of article
Selective Cleavage of tert-Butyldimethylsilylethers ortho to a Carbonyl Group by Ultrasound
Author/Authors
Alex H De Groot، نويسنده , , Roger A Dommisse، نويسنده , , Guy L.F. Lemière، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
9
From page
1541
To page
1549
Abstract
A general method for the selective cleavage of tert-butyldimethylsilylethers ortho to a carbonyl group is established by sonication of a 0.1 M solution of the substrate in 1/1 (v/v) CH3OH/CCl4. Other phenolic tert-butyldimethylsilylethers are unaffected. This reaction performed on flavanoids is completed within 3 h and no special workup is required. Other substrates are also investigated and a mechanism is proposed.
Keywords
Phenolics , Protecting groups , NMR , Sonochemistry
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1080630
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