Title of article :
A New Approach Towards the Synthesis of 3-Amino-6-(hetero)arylpyridazines Based on Palladium Catalyzed Cross-coupling Reactions
Author/Authors :
Bert U.W. Maes، نويسنده , , Guy L.F. Lemière، نويسنده , , Roger Dommisse، نويسنده , , Koen Augustyns، نويسنده , , Achiel Haemers، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
The synthesis of 3-amino-6-(hetero)arylpyridazines via palladium catalyzed cross-coupling reactions (Suzuki, Stille) on 3-amino-6-chloropyridazine (1a) and 3-amino-6-iodopyridazine (1b) has been investigated. Comparison of the results shows that there is no need to start from 1b. An improved method for the synthesis of compound 1b from 1a is also described.
Keywords :
palladium and compounds , Suzuki reactions , Stille reactions , pyridazines
Journal title :
Tetrahedron
Journal title :
Tetrahedron
