Title of article
Synthesis of Tertiary Cyclobutanols through Stereoselective Ring Expansion of Oxaspiropentanes Induced by Grignard Reagents
Author/Authors
Angela M Bernard، نويسنده , , Costantino Floris، نويسنده , , Angelo Frongia، نويسنده , , Pier P Piras، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
9
From page
4555
To page
4563
Abstract
The stereoselectivity of the ring expansion of oxaspiropentanes to cyclobutanols induced by Grignard reagents has been studied. It has been found that the reaction occurs through the intermediacy of a cyclobutanone, formed stereospecifically, whereas the attack of the Grignard reagent on the carbonyl group of the cyclobutanone is stereospecific only in the case of the oxaspiropentanes derived from aldehydes.
Keywords
Cyclopropanes , oxaspiropentanes , cyclobutanones , cyclobutanols , ring expansion , Grignard reagents , Stereoselectivity
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1080947
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