Title of article
Reaction of 5-(Trifluoromethyl)-2(5H)-furanone under Basic Conditions: Stereo-Controlled Michael Dimerization
Author/Authors
Takashi Okano، نويسنده , , Masayuki Chokai، نويسنده , , Shoji Eguchi، نويسنده , , Yoshio Hayakawa، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
6219
To page
6222
Abstract
Treatment of 5-trifluoromethyl-2(5H)-furanone under basic conditions gave a stereoisomeric mixture of two out of four possible stereoisomers of bis(trifluoromethyl)dihydro-2,4-bisfuranonyl depending on the reaction conditions. Butenolide anion generated with LDA is kinetically stable and reaction with 2-cyclohexenone stereoselectively gave a Michael adduct.
Keywords
Lactones , fluorine and compounds , Michael reactions , Stereochemistry
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1081119
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