• Title of article

    An Efficient Synthesis of 11β-(4-Aminophenyl)spiro[estr-4-ene-17β,2′(5′H)-furan]-3,5′-dione

  • Author/Authors

    Jens Geisler، نويسنده , , Arwed Cleve، نويسنده , , Michael Harre، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2000
  • Pages
    4
  • From page
    6489
  • To page
    6492
  • Abstract
    An efficient synthesis has been developed affording 11β-(4-aminophenyl)spiro[estr-4-ene-17β,2′(5′H)-furan]-3,5′-dione (2), main metabolite of antiprogestin (Z)-11β-[4-(dimethylamino)phenyl]-17β-hydroxy-17α-(3-hydroxyprop-1-enyl)estr-4-en-3-one (1), in an overall yield of 21%.
  • Keywords
    Hormones , Metabolites , Nitration , Steroids
  • Journal title
    Tetrahedron
  • Serial Year
    2000
  • Journal title
    Tetrahedron
  • Record number

    1081145