Author/Authors :
Alain Valla، نويسنده , , Zo Andriamialisoa، نويسنده , , Virginie Prat، نويسنده , , Alain Laurent، نويسنده , , Michel Giraud، نويسنده , , Roger Labia، نويسنده , , Pierre Potier، نويسنده ,
Abstract :
The methylene-de-oxo-bisubstitution reaction between dimethyl isopropylidene malonate and the C-15 β-methylenealdehyde 1 which could serve as substitute for E β-ionylideneacetaldehyde 2, produces stereoselectively the E,E olefin. Hence, new stereoselective syntheses of 13 E and 13 Z retinoic acids were described.
