Title of article
Synthesis of Chiral cis-1,2,3-Trisubstituted Aziridines
Author/Authors
Tuyen Nguyen Van، نويسنده , , Norbert De Kimpe، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
6
From page
7299
To page
7304
Abstract
Chiral cis-1,2,3-trisubstituted aziridines were conveniently synthesized from (1R,2S)-(−)- or (1S,2R)-(+)-norephedrine via the corresponding chiral N-(arylidene)-β-chloroamines. The enantiomeric purity of the chiral aziridines (e.e. >98%) was established by NMR spectroscopy utilizing (S)-(+)-1-(9-anthryl)-2,2,2-trifluoroethanol.
Keywords
N-(arylidene)-?-chloroamines , e.e. determination , chiral aziridines , NMR
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1081231
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