Indium-Mediated, Highly Efficient and Diastereoselective Addition of Cyclic Secondary Allylic Bromides to Carbonyl Compounds

Indium-mediated addition of 3-bromocyclohexene and 3-bromocyclooctene to a variety of aromatic aldehydes and cyclohexanone proceeds smoothly with excellent syn diastereoselectivity to produce the corresponding cycloalkenyl substituted homoallylic alcohols in good to high yields.