Title of article
Synthesis of a new structural analogue of (+)-porothramycin
Author/Authors
Anne Rojas-Rousseau، نويسنده , , Nicole Langlois، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
7
From page
3389
To page
3395
Abstract
A new phosphonate analogue of (+)-porothramycin has been synthesized from (S)-pyroglutaminol. Circular dichroism of diastereomeric intermediates 9 has been studied. The cytostatic activity of the new pyrrolo[2,1-c][1,4]benzodiazepine has been evaluated against human KB cells.
Keywords
4]benzodiazepines , phosphonate , circular dichroism , Cytotoxicity , Horner–Wadsworth–Emmons reaction
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1081924
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