Title of article
Heterolignanolides. Furo- and thieno-analogues of podophyllotoxin and thuriferic acid
Author/Authors
Angel C Ramos، نويسنده , , Rafael Pelaez Lamamie de Clairac، نويسنده , , Jose Luis L?pez، نويسنده , , Esther Caballero، نويسنده , , Manuel Medarde، نويسنده , , Arturo San Feliciano، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
15
From page
3963
To page
3977
Abstract
The conjugate addition–alkylation to 5H-furan-2-one followed by cyclization and controlled epimerizations have been applied to the synthesis of new furo- and thieno-lignan analogues. Podophyllotoxin and thuriferic acid heteroanalogues have been obtained by this methodology, as representative members of these families.
Keywords
Lignans , Thiophenes , antitumour compounds , Furans
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1081982
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