Title of article :
A convergent synthesis of (S)-β-methyl-2-aryltryptamine based gonadotropin releasing hormone antagonists
Author/Authors :
Thomas F Walsh، نويسنده , , Richard B. Toupence، نويسنده , , Feroze Ujjainwalla، نويسنده , , Jonathan R. Young، نويسنده , , Mark T. Goulet، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
A practical synthesis of (S)-β-methyl-2-aryltryptamine based gonadotropin releasing hormone antagonists which features a palladium-catalyzed Larock indole synthesis and a palladium-catalyzed Suzuki–Miyaura sequence to install the 2-position aryl substituent is reported.
Keywords :
Suzuki reactions , antagonists , Asymmetric synthesis , boron heterocycles , Indoles , Receptors , gonadotropin , Larock reactions
Journal title :
Tetrahedron
Journal title :
Tetrahedron
