Title of article
A convergent synthesis of (S)-β-methyl-2-aryltryptamine based gonadotropin releasing hormone antagonists
Author/Authors
Thomas F Walsh، نويسنده , , Richard B. Toupence، نويسنده , , Feroze Ujjainwalla، نويسنده , , Jonathan R. Young، نويسنده , , Mark T. Goulet، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
9
From page
5233
To page
5241
Abstract
A practical synthesis of (S)-β-methyl-2-aryltryptamine based gonadotropin releasing hormone antagonists which features a palladium-catalyzed Larock indole synthesis and a palladium-catalyzed Suzuki–Miyaura sequence to install the 2-position aryl substituent is reported.
Keywords
Suzuki reactions , antagonists , Asymmetric synthesis , boron heterocycles , Indoles , Receptors , gonadotropin , Larock reactions
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1082119
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