Title of article :
Application of triazenes for protection of secondary amines
Author/Authors :
Ryszard Lazny، نويسنده , , Michal Sienkiewicz، نويسنده , , Stefan Br?se، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
Use of the phenyldiazenyl group, which serves as a protecting group for secondary amines is described in detail. The triazene protected amine is compatible with oxidative and reductive conditions as well as with strong bases (LDA, tert-butyllithium) and alkylating reagents. The amine is regenerated by action of trifluoroacetic acid and a suitable reducing agent (EtOH or NaH2PO2).
Keywords :
amino acid and derivatives , amino ketones , triazenes , Protecting groups
Journal title :
Tetrahedron
Journal title :
Tetrahedron
