Title of article
Aziridine mediated asymmetric synthesis of α-benzylserine and α-n-butylserine
Author/Authors
Franklin A Davis، نويسنده , , Yulian Zhang، نويسنده , , Ashwin Rao، نويسنده , , Zhijun Zhang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
8
From page
6345
To page
6352
Abstract
Regioselective hydrogenolysis of enantiopure 2-benzyloxyaziridine 2-carboxylates represents a general method for the asymmetric synthesis of α-substituted serines. The aziridines are readily prepared via an aza-Darzens reaction of the enolate of methyl 3-benzyloxy-2-bromopropanoate with an enantiopure sulfinimine (N-sulfinyl imine).
Keywords
Asymmetric synthesis , Aziridines , ?-Amino acids , N-sulfinyl imines
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1082239
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