Title of article
Novel ring transformations of condensed [1,2,4]triazolo[4,3-b]pyridazine-6(5H)-one-3(2H)-thiones effected by dialkyl-acetylenedicarboxylates
Author/Authors
M?nika Sim?، نويسنده , , Antal Cs?mpai، نويسنده , , Veronika Harmat، نويسنده , , Orsolya Barabas، نويسنده , , G?bor Magyarfalvy، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
8
From page
7191
To page
7198
Abstract
On heating with dialkyl-acetylenedicarboxylates in DMF condensed [1,2,4]-triazolo[4,3-b] pyridazine-6(5H)-one-3(2H)-thiones undergo unprecedented ring transformations yielding novel tetracyclic 1,3-diazepines and thiazolotriazole derivatives depending on the applied reaction temperature. The observed substrate selectivity was interpreted on the basis of the results of comparative theoretical calculations carried out at semiempirical level (AM1).
Keywords
Ring transformation , substrate selectivity , Semiempirical calculations , Structure determination
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1082328
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