Title of article
Applications of Baylis–Hillman chemistry: enantioselective synthesis of (−)-methyl 3-aryl-2-methylene-3-(prop-2-yn-1-yloxy)propanoates via chiral leaving group strategy
Author/Authors
Deevi Basavaiah، نويسنده , , Nagaswamy Kumaragurubaran، نويسنده , , Duddu S Sharada، نويسنده , , Ravi Mallikarjuna Reddy، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
6
From page
8167
To page
8172
Abstract
Asymmetric synthesis of (−)-methyl 3-aryl-2-methylene-3-(prop-2-yn-1-yloxy)propanoates in 25–40% enantiomeric purities via the reaction of methyl (2Z)-3-aryl-2-(bromomethyl)prop-2-enoates with prop-2-yn-1-ol in the presence of quinidine is described.
Keywords
chiral leaving group , methyl 3-aryl-2-methylene-3-(prop-2-yn-1-yloxy)propanoates , Baylis–Hillman chemistry
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1082429
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