Title of article
A new highly stereoselective synthesis of cerebrosterol, an agonist of the nuclear receptor LXRs
Author/Authors
Xiang-Dong Zhou، نويسنده , , Wei-Shan Zhou، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
6
From page
8291
To page
8296
Abstract
The title compound, cerebrosterol 1, was synthesized stereoselectively (97% d.e.) in 41% overall yield from methyl hyodeoxycholanate 2 in 10 steps with desmosterol acetate 8 as the key intermediate and the modified Sharpless asymmetric dihydroxylation as the key step.
Keywords
cerebrosterol , Stereoselective , Sharpless AD reaction
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1082443
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