• Title of article

    A new highly stereoselective synthesis of cerebrosterol, an agonist of the nuclear receptor LXRs

  • Author/Authors

    Xiang-Dong Zhou، نويسنده , , Wei-Shan Zhou، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    6
  • From page
    8291
  • To page
    8296
  • Abstract
    The title compound, cerebrosterol 1, was synthesized stereoselectively (97% d.e.) in 41% overall yield from methyl hyodeoxycholanate 2 in 10 steps with desmosterol acetate 8 as the key intermediate and the modified Sharpless asymmetric dihydroxylation as the key step.
  • Keywords
    cerebrosterol , Stereoselective , Sharpless AD reaction
  • Journal title
    Tetrahedron
  • Serial Year
    2001
  • Journal title
    Tetrahedron
  • Record number

    1082443