Title of article
Effect of molecular sieves in the liquid-phase synthesis of nucleotides via the phosphoramidite method
Author/Authors
Yoshihiro Hayakawa، نويسنده , , Akiyoshi Hirata، نويسنده , , Jun-ichiro Sugimoto، نويسنده , , Rie Kawai، نويسنده , , Akira Sakakura، نويسنده , , Masanori Kataoka، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
8823
To page
8826
Abstract
It is demonstrated that the reaction of a nucleoside phosphoramidite and a nucleoside aided by a suitable promoter in the presence of molecular sieves 3A or 4A in a liquid phase is efficiently performed by the use of stoichiometric amounts of the reactants to give the desired coupling product in an excellent yield.
Keywords
Nucleotides , Phosphoramidites , Molecular sieves
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1082499
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