Title of article
Revision of the structure of haliclorensin to (S)-7-methyl-1,5-diazacyclotetradecane and confirmation of the new structure by synthesis
Author/Authors
Markus R Heinrich، نويسنده , , Yoel Kashman، نويسنده , , Peter Spiteller، نويسنده , , Wolfgang Steglich، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
6
From page
9973
To page
9978
Abstract
A reinvestigation of the marine alkaloid haliclorensin led to a revision of the proposed structure to 7-methyl-1,5-diazacyclotetradecane. The new structure was confirmed by total synthesis of both optical forms. According to chiroptical measurements and GC–MS investigations, natural haliclorensin consists of a 3:1 mixture of the (S)- and (R)-enantiomers.
Keywords
marine metabolites , Alkaloids , Metathesis , haliclorensin , Stereochemistry
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1082619
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