Title of article
Novel synthesis of 1,2,4-triazolo[4,3-a]pyrimidin-5-one derivatives
Author/Authors
Hamdi M Hassaneen، نويسنده , , Hyam A Abdelhadi، نويسنده , , Tayseer A Abdallah، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
6
From page
10133
To page
10138
Abstract
1,2-Dihydro-2-thioxopyrimidin-4(3H)ones 6 react with C-ethoxycarbonyl-N-arylhydrazonoyl chlorides 1 to give 1,2,4-triazolo[4,3-a]pyrimidines 11 in good yield. The latter products 11 react with benzenediazonium chloride, nitrous acid, acetyl chloride and chloroacetyl chloride to give the corresponding substitution products 16–18. The structures of the newly synthesized compounds are established on the basis of chemical and spectroscopic evidence.
Keywords
1 , 2-dihydro-2-thioxopyrimidin-6-phenylamino-4(3H)ones , C-ethoxycarbonyl-N-arylhydrazonoyl chlorides , 2 , 1 , 3-a]pyrimidine-5-ones
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1082637
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