Title of article :
A mechanistic study of the ammonolysis of alkyl acetoacetates in water. Formation of 1,5-dimethyl-2,6,9-triaza-bicyclo[3.3.1]nonane-3,7-dione as the main product
Author/Authors :
Rodrigo Paredes، نويسنده , , Rodrigo Abonia، نويسنده , , John Cadavid، نويسنده , , Rodolfo Moreno-Fuquen، نويسنده , , Alonso Jaramillo، نويسنده , , Angelina Hormaza، نويسنده , , Alfonso Ramirez، نويسنده , , Allan Kennedy، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
Ammonolysis of alkyl acetoacetates with 15% NH3 in water at room temperature initially lead to formation of alkyl β-aminocrotonates which slowly converted into 1,5-dimethyl-2,6,9-triaza-bicyclo[3.3.1]nonane-3,7-dione as the main product.
Keywords :
acetoacetates , Ammonolysis , enol mechanism , ?-aminocrotonates , Heterocycles
Journal title :
Tetrahedron
Journal title :
Tetrahedron
