Title of article
Synthesis of allenes by double Horner–Wadsworth–Emmons reaction
Author/Authors
Hideki Inoue، نويسنده , , Hiroshi Tsubouchi، نويسنده , , Yasuo Nagaoka، نويسنده , , Kiyoshi Tomioka، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
8
From page
83
To page
90
Abstract
LDA treatment of aldehydes or ketone with alkenylphosphonates , prepared by Horner–Wadsworth–Emmons (HWE) reaction of methylenebisphosphonate with aldehydes, afforded Baylis–Hillman reaction-type products in high yields. HWE olefination of with KH or KH-18-crown-6 as a base provided allenes in good yields. One-flask procedure was successfully developed starting from to afford an allene in a reasonably good yield.
Keywords
alkenylphosphonates , Olefination , Allenes
Journal title
Tetrahedron
Serial Year
2002
Journal title
Tetrahedron
Record number
1082679
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