• Title of article

    Synthesis of the proton-ionizable lariat crown ether and chiral recognition of primary amines

  • Author/Authors

    Kazunori Tsubaki، نويسنده , , Masafumi Zeze and Hiroyuki Tanaka، نويسنده , , Takayoshi Kinoshita، نويسنده , , Kaoru Fuji، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    6
  • From page
    1679
  • To page
    1684
  • Abstract
    An optically active proton-ionizable lariat crown ether derivative was prepared. Host displays enantiomeric selectivity toward phenylglycinol (Klarge/Ksmall=3.2) and phenylalaninol (Klarge/Ksmall=1.7). The key intermediate was synthesized in two steps from commercially available binaphthol in 30% yield.
  • Keywords
    amino alcohol , Crown ether , 1 , 1?-binaphthyl , Chiral recognition
  • Journal title
    Tetrahedron
  • Serial Year
    2002
  • Journal title
    Tetrahedron
  • Record number

    1082848