Title of article
A convergent synthesis of the spiroketal moiety of the HIV-1 protease inhibitors didemnaketals
Author/Authors
Yan Xing Jia، نويسنده , , Xin Li، نويسنده , , Bin Wu، نويسنده , , Xue Zhi Zhao، نويسنده , , Yong-Qiang Tu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
12
From page
1697
To page
1708
Abstract
The stereoselective synthesis of the spiroketal fragment and its C1″-epimer of the HIV-1 protease inhibitors didemnaketals has been carried out through multisteps from the natural (R)-(+)-pulegone, which involved the diastereoselective construction of four chiral carbon centers by intramolecular chiral induction.
Keywords
spiroketal moiety , intramolecular chiral induction , HIV-1 protease
Journal title
Tetrahedron
Serial Year
2002
Journal title
Tetrahedron
Record number
1082851
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