Title of article
New glycosyl α-hydroxyesters as key intermediates in a convenient route to glycosyl α-aminoester chirons
Author/Authors
Claude Grison، نويسنده , , Frédéric Coutrot، نويسنده , , Philippe Coutrot، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
7
From page
2735
To page
2741
Abstract
This article examines the stereoselective preparation of glycosyl α-hydroxyesters via the asymmetric reduction of glycosyl α-ketoesters, using various chiral or achiral reagents and Bakersʹ yeast. The diastereomeric excess could exceed 98% for the galacto-series. These glycosyl α-hydroxyesters are used as chiral precursors for the diastereoselective synthesis of glycosyl α-aminoesters synthons.
Keywords
Sodium cyanoborohydride , catecholborane–oxazaborolidine , Sodium azide , glycosyl ?-hydroxyester , glycosyl ?-ketoester , Bakersי yeast , glycosyl ?-aminoester
Journal title
Tetrahedron
Serial Year
2002
Journal title
Tetrahedron
Record number
1082943
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