Diterpenylated and prenylated flavonoids from Macaranga denticulata

An O-methylated analogue of macarangin () and denticulaflavonol () which possesses a diterpene substituent have been isolated along with other compounds from the leaves of Macaranga denticulata. Their detailed 1D and 2D spectral analysis are reported. The radical scavenging properties of compounds were evaluated. Among the compounds tested, showed a pronounced antioxidant activity (IC50 0.032±0.001 mM).