Title of article
On the mechanism of reaction between ketones and nitriles. Unexpected results from benzyl nitriles
Author/Authors
Antonio Herrera، نويسنده , , Roberto Mart??nez-?lvarez، نويسنده , , Pedro Ramiro، نويسنده , , Mourad Chioua، نويسنده , , Rosario Torres، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
10
From page
3755
To page
3764
Abstract
Benzyl nitriles bearing electron donating groups react with ketones in the presence of trifluoromethanesulfonic anhydride to form naphthalene amines and related compounds. In contrast, the same benzyl nitriles substituted with electron withdrawing groups form the corresponding 2,4-dibenzyl substituted pyrimidines. A mechanism is proposed that explains the divergence in reaction paths leading to these products.
Keywords
triflic anhydride , benzyl nitriles , naphthalene amines , benzyl pyrimidines
Journal title
Tetrahedron
Serial Year
2002
Journal title
Tetrahedron
Record number
1083057
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