Author/Authors :
Stefano Chimichi، نويسنده , , Marco Boccalini، نويسنده , , Barbara Cosimelli، نويسنده , , Giampietro Viola، نويسنده , , Daniela Vedaldi، نويسنده , , Francesco DallʹAcqua، نويسنده ,
Abstract :
An efficient synthesis (yields >70%) of linear 7H-furo[3,2-g]chromen-7-one derivatives (psoralens or furocoumarins) has been carried out starting from ring-substituted 2-(coumarin-7-yl)oxyaldehydes; moreover, the phototoxicity of these compounds has been tested on a cultured cell line of murine fibroblast.
Keywords :
psoralens , furocoumarins , Phototoxicity , Coumarin derivatives