Author/Authors :
John T Gupton، نويسنده , , Stuart C Clough، نويسنده , , Robert B Miller، نويسنده , , Bradley K Norwood، نويسنده , , Charles R Hickenboth، نويسنده , , Itta Bluhn Chertudi، نويسنده , , Scott R Cutro، نويسنده , , Scott A Petrich، نويسنده , , Fred A Hicks، نويسنده , , Douglas E. Wilkinson، نويسنده , , James A. Sikorski، نويسنده ,
Abstract :
A variety of vinylogous iminium salt derivatives have been examined as useful precursors for the regiocontrolled synthesis of heterocyclic appended pyrazoles. The reaction conditions for such processes have been optimized and the regiochemical preferences have been determined. Such reaction sequences represent methodologies which may have useful applications for the preparation of biologically interesting substances.
Keywords :
vinamidinium salts , chlorovinyl aldehydes , chloropropeniminium salts , Pyrazoles