Title of article
Biosynthetic studies of the tetramic acid antibiotic trichosetin
Author/Authors
Eufrocinio C Marfori، نويسنده , , Takeshi Bamba، نويسنده , , Shin-ichiro Kajiyama، نويسنده , , Ei-ichiro Fukusaki، نويسنده , , Akio Kobayashi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
6655
To page
6658
Abstract
A feeding experiment with 13C-labeled precursors was conducted in the dual cultures of Trichoderma harzianum H14 and Catharanthus roseus callus to determine the biosynthetic origin of the carbon atoms in trichosetin. Results showed that trichosetin originated from two separate biogenetic units. One unit is an octaketide intermediate directly derived from eight intact acetate units joined in a head-to-tail fashion of a polyketide pathway. The other unit is serine.
Keywords
Trichoderma harzianum , trichosetin , Polyketide , tetramic acid , Biosynthesis , Catharanthus roseus , dual culture
Journal title
Tetrahedron
Serial Year
2002
Journal title
Tetrahedron
Record number
1083359
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