Title of article
Towards nucleopeptides containing any trifunctional amino acid (II)
Author/Authors
Laurent Debéthune، نويسنده , , Vicente March?n، نويسنده , , Gemma Fàbregas، نويسنده , , Enrique Pedroso، نويسنده , , Anna Grandas، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
14
From page
6965
To page
6978
Abstract
Nucleopeptides with no restriction in the amino acid composition can be synthesized using stepwise solid-phase methodology. Best conditions for the protection of arginine and cysteine, as well as for the final deprotection treatment are established, and our conclusions can be extended to the preparation of any peptide–oligonucleotide hybrid. The association between certain side reactions and nucleopeptide sequences is also discussed.
Keywords
cysteine , Protection , nucleopeptide , Asparagine , Arginine
Journal title
Tetrahedron
Serial Year
2002
Journal title
Tetrahedron
Record number
1083397
Link To Document