Author/Authors :
Yuki Tachibana، نويسنده , , Naoki Matsubara، نويسنده , , Fumio Nakajima، نويسنده , , Tetsuro Tsuda، نويسنده , , Sakae Tsuda and Yasushi Mitsuishi، نويسنده , , Kenji Monde، نويسنده , , Shin-ichiro Nishimura، نويسنده ,
Abstract :
An efficient synthetic method of sequential glycopeptide-polymer by means of the combined chemical and enzymatic strategy was applied to the practical synthesis of some tandem repeating mucin-type glycoproteins. Versatility of the present synthetic strategy was demonstrated by elucidating some physicochemical and conformational analyses of these synthetic mucins.
Keywords :
Mucins , tandem-repeating glycoproteins , Multivalency , Cluster effect , sialyl T antigenic glycoproteins
