Title of article :
Double thioalkylation/arylation of nitroarenes with the reduction of nitro- to amino group
Author/Authors :
Zbigniew Wr?bel، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
Some active bicyclic nitroarenes readily react with an excess of alkyl/arylthiols in the presence of DBU and bis-trimethylsilylacetamide (BSA) in DMF solution, to give dithioalkyl/aryl substituted anilines in moderate to good yields via displacement of ortho- and para-hydrogen atoms with simultaneous reduction of the nitro- to amino-group.
Keywords :
Amines , Reduction , bicyclic aromatic compounds , Thiols , Substitution
Journal title :
Tetrahedron
Journal title :
Tetrahedron